The Brisbane and South Coast Hospitals Board was constituted under the "Hospitals Act of 1923". The Act establishing the board was assented to on 23 November 1923 and members were appointed on 15 May 1924. Areas covered included the cities of Brisbane and South Brisbane; the towns of Coolangatta, Hamilton, Ithaca, Redcliffe, Sandgate, Southport, Toowong, Windsor and Wynnum; the shires of Balmoral, Beenleigh, Belmont, Caboolture, Cleveland, Coomera, Coorparoo, Enoggera, Kedron, Moggill, Nerang, Pine, Sherwood, Stephens, Tambourine, Taringa, Tingalpa, Toombul, Waterford and Yeerongpilly.
The Board was charged with the maintenance, management and regulation of all hospitals within its geographical boundary.
Initially, the membership of the board was determined by:
a) the election of 3 members by the contributors to any hospital within the district
b) the appointment of 3 members by the Governor in Council
c) the election of 3 members by Local Authorities according to the following formula:- the Brisbane City Council elected 1 member; the councils of the cities, towns and shires of South Brisbane, Hamilton, Ithaca, Sandgate, Toowong, Windsor, Wynnum, Balmoral, Belmont, Coorparoo, Enoggera, Kedron, Moggill, Sherwood, Stephens, Taringa, Toombul and Yeerongpilly as a group elected by ballot 1 member; the councils of the towns and shires of Coolangatta, Redcliffe, Southport, Beenleigh, Caboolture, Cleveland, Coomera, Nerang, Pine, Tambourine, Tingalpa and Waterford as a group elected 1 member.
Home Secretary,15 May 1924 - 5 Dec 1935
Secretary for Health and Home Affairs, 5 Dec 1935 - 12 Aug 1957
Minister for Health and Home Affairs, 12 Aug 1957 - 6 Jun 1959
An order in council was published on 13 June 1959 stating that the part of the Brisbane and South Coast Hospitals comprising that part of the City of Brisbane south of the Brisbane River, the Shire of Beaudesert and the Shire of Redland shall be excluded from the current district and be constituted as a new district called the "South Brisbane Hospitals Board". The remaining portion of the Brisbane and South Coast Hospitals Board was then renamed as the "North Brisbane Hospitals Board". The board was responsible for the ten hospitals within its geographical boundary.